Proline & Hair Growth – Mechanism of Action

Divi’s Scalp Serum is scientifically formulated to improve scalp health, mitigate hair loss, and promote hair growth. To do this, key am ino acids, such as proline, are on the list of crucial ingredients. Proline facilitates cell development and collagen fibril formation, both of which can promote healthy hair in various ways.

This article will help you better understand exactly how the advantages of proline work in Divi’s Scalp Serum, Shampoo & Conditioner.

Proline: How Does it Help with Hair Growth?

Proline, otherwise known as L-proline or hydroxyproline, is an amino acid. Amino acids build muscles, facilitate chemical reactions, and transport nutrients. Proline has two main functions: to aid the general function of cells; and to make key proteins, such as collagen.

These functions are key since hair, like other bodily components, relies on cell development to grow. Your body can use the amino acids found in collagen to build hair proteins, strengthen the skin that contains hair roots, and prevent follicle damage.

The cell wall’s synthesis and composition adapt in response to environmental stress and signals. In light of this, cell wall proteins controlling cell shape and elongation are key to cell proliferation. As part of this process, proline can positively impact root hair growth and root hair length.

Which Hair and Scalp Conditions Can Proline Help?

 Research suggests proline can positively impact the following conditions:

• Dandruff – Dandruff is an incredibly common hair condition, and can often feel embarrassing. Put simply, dandruff flakes are dead skin cells caused by fungal growth. The faster the scalp sheds the dead skin, the worse the condition becomes. Proline purifies, regenerates, and renews scalp cells.
• Scalp eczema – This is a form of atopic dermatitis that causes dry, inflamed and itchy skin. When incorporated with other ingredients, proline is useful for combating scalp eczema.
• Irritant dermatitis – When an irritant damages your skin’s outer protective layer, the result is a non-allergic skin reaction; this is known as irritant dermatitis. During the process of keratinocyte differentiation, plasma membranes are replaced with the cornified envelope. This envelope is made of structural proteins, such as loricrin, involucrin and small proline-rich proteins. The cornified envelope prevents the passage of irritants and microbes through the epidermis.
• Allergic dermatitis – Proline’s function in combating allergic dermatitis is effectively the same as its function for treating irritant dermatitis. The cornified envelope can also prevent the passage of allergens through the epidermis.
• Androgenetic alopecia – As stated earlier, proline assists collagen formation. In addition, proline is the primary component of keratin. So, the intake of proline-rich collagen should give your body what it needs to grow hair and slow down or prevent androgenetic alopecia, which is also known as female- or male-pattern baldness.
• Thinning hair – Proline hydroxylation and O-glycosylation (or HRGPs) are essential for driving root hair growth.
• Post-pregnancy – After giving birth, many new moms may notice significant hair loss due to a drop in estrogen levels. A boost in proline boosts the production of collagen and keratin.
• Thyroid disease – This is a medical condition in which the gland produces either too much (hyperthyroidism) or too little (hypothyroidism) thyroid hormone. Amino acid deficiency can be a causal factor and a symptom of hypothyroidism.  
• Alopecia and alopecia subtypes – Alopecia is a type of sudden hair loss. It has many variants, such as alopecia areata, traction alopecia and frontal fibrosing alopecia. When blended with other ingredients, proline can fight this condition.

Can Too Much Proline Affect Hair Growth?

There is still a lack of research on how excessive amounts of proline can affect hair growth. This is why Divi’s Scalp Serum contains a measured amount of proline. The amount in our Scalp Serum is clinically proven to be safe.

What is the Function of Collagen?

Collagen is a protein accounting for around 30% of your body’s total protein. In the context of hair growth, it helps fibroblasts form in the middle skin layer, which aids cell reproduction.

Here are five ways collagen can help your hair.

Provides Amino Acids Used to Grow Hair

Amino acids are required to build keratin, which is the primary protein making up hair. Proline is the main component of keratin, so Divi’s Scalp Serum has been formulated with this ingredient to support the best conditions for keratin development. 

Combats Hair Follicle Damage

Collagen has antioxidant properties and can fight damage to follicles caused by free radicals. Although our bodies are naturally able to combat free radicals, this decreases with age and we need all the help we can get.

Preliminary research shows collagen can fight up to four different types of free radicals that have the potential to damage hair follicles, which in turn will inhibit hair growth. Research has found that collagen is likely to be even more effective at fighting free radicals than tea compounds.

Prevents Thinning Due to Age

Collagen protects the layers of skin that house the roots of your hair. Research on this topic is not yet available, although it is generally assumed that collagen makes up 70% of your dermis skin layer, so you can expect the benefits of collagen to extend to your hair roots, preventing hair from falling out as the skin ages.

Potential for Slowing Hair-Graying

Free radical damage can cause hair to become gray due to damage to hair follicles. Since collagen is an antioxidant, it can curb the occurrence of graying hair. Although collagen is not able to reverse graying, results from studies conducted in the lab show promising potential for collagen to slow down the graying process.

Can Form Part of Your Daily Routine

Collagen is found in many common foods, such as animal meat or bone broth, and it also occurs naturally in the skin. Divi’s Shampoo, Conditioner and Scalp Serum contain proline, which stimulates collagen production.

How Often Can I Use Proline on My Hair?

Proline is normally balanced in the body through a healthy diet. Cabbage, peanuts and soy are good sources of proline.

Supplementation through topical application of Divi’s Scalp Serum once a day can also provide targeted support to ensure proline levels are balanced with the other complementary ingredients. The combination of proline with these ingredients helps create an optimal environment for scalp health and hair growth.

Why Choose Divi?

Divi uses science-backed, dermatologist-approved ingredients to bring you the best hair products on the market. The active ingredients in Divi’s Scalp Serum, Shampoo & Conditioner are vegan and cruelty-free, and these clean hair care products can be used daily for the best results without risking any adverse effects on your hair or scalp. All three include proline as a crucial ingredient to caring for your scalp.

Final Thoughts

Although hair care products are made with the objective of improving your hair and scalp health, your lifestyle and genetics still play an important role in determining how effective they’ll be. Do your best to make sure that you exercise regularly, maintain a balanced diet, and kick potentially harmful habits, such as smoking and drinking alcohol.

The innovative blends in Divi’s lineup scalp products – our Scalp Serum, Shampoo & Conditioner – are specifically designed to help improve hair health by leveraging high-quality ingredients, like proline.